Description

Human RSV ImmuneSelect is a peptide pool composed of 42 peptides that include MHC-I and MHC-II epitopes from Human respiratory syncytial virus A2 and Human orthopneumovirus. Peptide sequences are collected from the Nucleoprotein, Fusion glycoprotein, Matrix protein, Non-structural protein 1 and RNA polymerase.

The purity of each peptide is ≥95% (HPLC-MS).

Application

The in-vitro stimulation of Peripheral Blood Mononuclear Cells (PBMCs) with RSV ImmuneSelect activates memory T-cells specific to the virus, leading to cytokine secretion and the increased expression of specific surface markers. These biomarkers can be detected using various techniques: ELISpot kits quantify cytokine-producing cells, while flow cytometry measures cells expressing these specific surface markers.