Description

Lyme Disease ImmuneSelect is a peptide pool composed of 41 peptides that cover MHC-II restricted epitopes of Borreliella burgdorferi (Lyme Disease Borrelia). Peptide sequences are derived from:

• Borrelia P83/P100 antigen
• Histidine kinase
• Immunogenic protein P37
• Outer surface protein A
• Outer surface protein C

The purity of each peptide is ≥95% (HPLC-MS).

Application

The in-vitro stimulation of Peripheral Blood Mononuclear Cells (PBMCs) with Lyme Disease ImmuneSelect Peptide Pool activates memory T cells specific to the infection, leading to cytokine secretion and the increased expression of specific surface markers.